Treatments

Using Norco for Chronic Pain Management

Source: Drugs.com
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What is Norco?

Norco is a drug that contains both acetaminophen and hydrocodone to alleviate severe pain. Acetaminophen is a less severe pain-killer that heightens the functions of hydrocodone. Hydrocodone is an opioid pain medication also known as a narcotic. Norco interferes with the pain signals to the brain. 

What are the side effects of Norco?

The common side effects from using hydrocodone include: dry mouth, constipation, stomach ache, headache, dizziness, mild drowsiness, and blurred vision.


The severe side effects from using hydrocodone include: Weak or shallow breathing, confusion, seizures, easy brusising, severe drowsiness, infertility, impotence, nausea, dizziness, jaundice, clay-colored stools, dark urine, vomiting, and lightheadedness. If you experience any of these side effects contact your healthcare provider immediately.


Severe side effects of hydrocodone can lead to addiction, overdose, or even death. Avoid mixing alcohol and hydrocodone to prevent any severe side effects from the drug. Acetaminophen can cause liver damage or even death so contact healthcare provider if you notice any pain in upper stomach, loss of appetite, dark urine, itching, jaundice, skin redness, or spreading rash, or clay colored stools. 

Norco Interactions

Understand the side effects of fentanyl with other drugs you might be already prescribed such as depression medication, Parkinson’s disease, migraine headaches, serious infections can cause serious conditions such as serotonin syndrome. Avoid the use of Norco if you have used MAO inhibitor within the past 14 days. MAO inhibitors include: isocarboxaxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. The other narcotic medication, prescription cough medication, and drugs that reduce your breathing or make you sleepy can also interfere with fentanyl causing serious side effects.


The common drugs that interfere with Norco: Ambien (zolpidem), Aspirin, Baclofen, Clonazepam, Cymbalta (duloxetine), Flexeril (cyclobenzaprine), Gabapentin, Ibuprofen, Levothyroxine, Lisinopril, Lyrica (pregabalin), Metformin, Neurontin (gabapentin), Omeprazole, Prednisone, Synthroid (levothyroxine), Tramadol, Trazodone, Vitamin D3 (cholecalciferol), and Xanax (alprazolam).

Patient Tips

Patients are only recommended to use Narco short term due to the severe side effects. There are two different types of Norco: 1. The strength includes 7.5mg of hydrocodone and 325mg of acetaminophen, 2. The strength includes 10mg of hydrocodone and 325 mg acetaminophen. The drug can cause impair effects and drowsiness which can effect your ability to drive or operate machinery.