Opioid Epidemic

# What Does Milligram Morphine Equivalents (MME) Mean? Print
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Morphine milligram equivalents (MME), or morphine equivalent doses (MED), is a value used to compare the potency of an opioid dose relative to morphine.

MME is determined by multiplying the dose of a prescribed opioid by the number of times it is taken in a day. That total is then multiplied by a conversion factor for that specific opioid relative to morphine. For example:

• Codeine 30 mg × 4 times a day = 120 × 0.15 (conversion for codeine) = 18 MME
• Oxycodone 5 mg × 4 times a day = 20 × 1.5 (conversion for oxycodone) = 30 MME
• Hydromorphone 4 mg × 4 times a day = 16 × 4 (conversion for hydromorphone) = 64 MME.

To figure out the total MME if an individual is taking more than one opioid, calculate the MME for each medication and then add the MMEs together. A list of conversion factors can be found at Utah Department of Health, Medicaid. There are also opioid calculators that can help, such as Practical Pain Management’s opioid calculator.

#### Opioid doses equivalent to 1 mg of morphine

Note: Conversions that do not equate exactly to 1 mg of morphine are noted in parentheses. Conversions were made with the Oregon Pain Guidance opioid conversion calculator.

• Codeine – 7 mg (1.05 morphine)
• Fentanyl transdermal – 0.4 mcg/hr (0.96 morphine)
• Hydrocodone – 1 mg
• Hydromorphone – 0.25 mg
• Oxycodone – 0.65 mg (0.975 morphine)
• Oxymorphone – 0.35 mg (1.05 morphine)